c rel Proto Oncogenes
《英文msh詞典》c rel Proto Oncogenes
[入口詞] c rel Proto Oncogenes
[主題詞] Genes,rel
[英文釋義] Family of retrovirus-associated DNA sequences (v-rel) originally isolated from an avian reticuloendotheliosis virus strain. The proto-oncogene rel (c-rel) codes for a subcellular (nuclear and cytoplasmic) transcription factor that has a role in lymphocyte differentiation. Translocation or overexpression of c-rel or competition from v-rel causes oncogenesis. The human rel gene is located at 2p12-13 on the short arm of chromosome 2.